名称：(2s,6r)-2,6-二甲基哌啶-4-酮
英文名称：(2s,6r)-2,6-dimethylpiperidin-4-one
分子式：c7h13no
分子量: 127.18
cas no.：13200-35-6
结构式：
规格：95%
用途：基础原料、有机中间体、医药中间体
合成路线如下：
hydrogen; ethanol; 5 palladium over charcoal
reactants are commercially availlable.
elan pharmaceuticals, inc., wo2007/64914, a2, (2007) synthesis of trans-2,6-dimethylpiperidin-4-one (93). trans-n-benzyl-2,6-dimethylpiperidin-4-one (91; 7.5 g) was dissolved in etoh (20 ml) and the catalyst (0.8 g, pd/c 5percent) was added. the slurry was vigorously stirred and kept under a hydrogen atmosphere (60 psi) for 90 hr. the catalyst was rem oved by filtration through celite and the filtrate was evaporated at 3 mmhg/40 °c. the residue (ca. 5.2 g) was used without further purification.