吡咯用从氯仿和naoh反应而来的二氯卡宾处理发生环丙烷化,接着重排生成3-氯吡啶。


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反应机理


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反应实例


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参考文献


1. ciamician, g. l.; dennsted, m. ber. 1881, 14,1153.

2. wynberg, h. chem. rev. 1960,60, 169-184. (review).

3. wynberg, h. and meijer, e.w. org. react. 1982, 28, 1-36. (review).

4. parham, w. e.; davenport, r.w.; biasotti, j. b. j. org. chem. 1970, 35, 3775-3779.

5. král, v.; gale, p. a.;anzenbacher, p. jr.; k. jursíková; lynch, v.; sessler, j. l. chem. comm. 1998, 9-10.

6. pflum, d. a. ciamician–dennstedrearrangement. in name reactions in heterocyclic chemistry; li, j. j.,ed.; wiley: hoboken, nj, 2005, pp 350-354. (review).


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