分子量: 211.26
cas no.:198835-06-2
结构式:
规格:95%
用途:基础原料、有机中间体、医药中间体
合成路线如下:
diborane;
reactants are commercially availlable.
slade, david j., us2011/144150, a1, (2011) in a method analogous to j.malpass and c. cox, tetrahedron lett., 1999, 40, 1419-1422, tert-butyl 2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate is treated with diborane to afford a mixture of alcohols w hich is separated by chromatography.the desired alcohol tert-butyl 5-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate is then oxidized using the swern procedure to afford the title compound.
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